Scleromyxedema: A Case Report with Cutis-Laxa like Features

A 75 year-old woman who reports eight months of painful lesions located in her face (Figure 1) back and thighs. On physical examination she presented multiple erythematous plaques and grouped papules, as well as skin infiltration, highlighting the presence of excessive folding on the back and posterior areas of both thighs (Figure 2). Several skin biopsies showed a normal epidermis, dermis with diffuse mucinosis, and numerous fibroblasts and scattered histiocytes without atypia, consistent with scleromyxedema. Protein electrophoresis and immunofixation in blood were compatible with multiple myeloma. This study was performed at Red Salud UC-Christus, Santiago, Chile by the Department of Dermatology. The patient was referred to a hemato-oncologist of our institution for the treatment of her myeloma. She allowed us to publish her case. Discussion